Top 9 where is celebrex metabolized THE BEST

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1.Clinical pharmacokinetics and pharmacodynamics of celecoxib

  • Author: pubmed.ncbi.nlm.nih.gov
  • Post date: 11 yesterday
  • Rating: 5(362 reviews)
  • Highest rating: 4
  • Low rated: 2
  • Summary: Celecoxib is metabolised primarily by the cytochrome P450 (CYP) 2C9 isoenzyme and has an elimination half-life of about 11 hours in healthy individuals. Racial …

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2.Celecoxib Pathway, Pharmacokinetics – PharmGKB

  • Author: www.pharmgkb.org
  • Post date: 9 yesterday
  • Rating: 5(1012 reviews)
  • Highest rating: 5
  • Low rated: 2
  • Summary: It is extensively metabolized in the liver with very little drug (<3%) being eliminated unchanged (PMID: 10681375). The major routes of excretion for celecoxib …

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3.Celecoxib: Uses, Interactions, Mechanism of Action | DrugBank Online

  • Author: go.drugbank.com
  • Post date: 27 yesterday
  • Rating: 2(726 reviews)
  • Highest rating: 5
  • Low rated: 3
  • Summary: A large part of celecoxib metabolism is mediated by cytochrome P450 2C9 in the liver with some contribution from CYP3A4 and CYP2C8 and possible …
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4.Metabolism and Excretion of [14C]Celecoxib in Healthy Male …

  • Author: dmd.aspetjournals.org
  • Post date: 10 yesterday
  • Rating: 3(642 reviews)
  • Highest rating: 4
  • Low rated: 1
  • Summary:

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5.[PDF] CELEBREX® – Accessdata.fda.gov

  • Author: www.accessdata.fda.gov
  • Post date: 29 yesterday
  • Rating: 4(1074 reviews)
  • Highest rating: 4
  • Low rated: 3
  • Summary: Celecoxib is eliminated predominantly by hepatic metabolism with little (< 3%) unchanged drug recovered in the urine and feces. Following a single oral dose of …

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6.[PDF] center for drug evaluation and research – Accessdata.fda.gov

  • Author: www.accessdata.fda.gov
  • Post date: 8 yesterday
  • Rating: 2(1224 reviews)
  • Highest rating: 4
  • Low rated: 1
  • Summary: Metabolism: Celecoxib metabolism is primarily mediated via cytochrome P450 2C9. Three metabolites, a primary alcohol, the corresponding carboxylic acid and …

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7.Celecoxib – an overview | ScienceDirect Topics

  • Author: www.sciencedirect.com
  • Post date: 22 yesterday
  • Rating: 5(1777 reviews)
  • Highest rating: 5
  • Low rated: 1
  • Summary: Celecoxib is metabolized extensively in the liver predominantly via cytochrome P-450 2C9 to three inactive metabolites. The elimination of celecoxib is via …

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8.Celecoxib – Wikipedia

  • Author: en.wikipedia.org
  • Post date: 3 yesterday
  • Rating: 4(756 reviews)
  • Highest rating: 4
  • Low rated: 2
  • Summary: Celecoxib ; Liver (mainly CYP2C9) · 7.8 hours; 11 hours (mild hepatic impairment); 13 hours (moderate-severe hepatic impairment) · Faeces (57%), urine (27%).

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9.Pharmacokinetics, metabolism and excretion of celecoxib, a …

  • Author: onlinelibrary.wiley.com
  • Post date: 1 yesterday
  • Rating: 2(1633 reviews)
  • Highest rating: 4
  • Low rated: 2
  • Summary:

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